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By William Dudley

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Adverse event effects of SSRI drugs make their use hardly justified in the majority of cases because SSRIs are well known to have limited efficacy over placebo and . . non-pharmacologic treatments. ” —Donald Marks, testimony before an FDA advisory panel on antidepressants, February 3, 2004. Marks is a physician who previously worked as director of clinical research for two multinational pharmaceutical companies. “ In practice, in the treatment of major depression, I almost always combine medicine with psychotherapy.

The National Institute of Mental Health (NIMH) is a federal government agency that oversees government policy and research on mental health issues. “ Anyone who has been on an antidepressant for more than about a month can experience withdrawal symptoms and dependence if the drug is stopped abruptly. ” —Joseph Glenmullen, The Antidepressant Solution. New York: Free Press, 2005. Glenmullen is a practicing psychiatrist, a clinical instructor at Harvard Medical School, and the author of several books including Prozac Backlash.

But Still Sad; Antidepressants Aren’t the Magic That Millions Hoped,” Los Angeles Times, March 27, 2006. Susan, a teacher and mother, took the antidepressant Paxil for several years to combat anxiety and depression but stopped taking it after she developed unpleasant physical symptoms. ’ ” —Richard Kapit, quoted in David Stipp, “Trouble in Prozac,” Fortune, November 28, 2005. Kapit is a former FDA official who oversaw the safety review of Prozac prior to its 1987 FDA approval; he now works as a medical writer and consultant.

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