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By Bryan C. Hains

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The exact mechanism of their action is not known, but they are thought to help limit changes in blood vessel tone. Beta-blockers are the most widely used preventative drugs. They block the effects of substances that are normally present, such as epinephrine (adrenaline), that excite the heart and blood vessels. Beta-blockers reduce these effects, acting on the heart and blood vessels to cause vascular contraction. Interactions have also been established for beta-blockers and the 5-HT system. Calcium-channel blockers act on small pores of thin muscles that wrap around blood vessels and allow entry of calcium ions into the cell.

These results can be useful for people considering whether or not to begin a family and potentially pass the gene along to their children. Huntington’s Disease PATHOLOGICAL CHANGES HD causes identifiable anatomical changes in the brain. Like people with Parkinson’s disease, patients with HD exhibit degenerative changes within the basal ganglia, a cluster of midbrain nuclei that play a part in the control of muscle movements. In particular, the caudate and putamen structures (collectively known as the striatum) are involved in the planning and modulation of movement signals.

There are many varieties of headaches, each with different causes and symptoms. ciated with tension headaches is generally restricted to the outside of the head, often described as band-like and symmetrical. Tension headaches can be classified depending on how often they occur: episodic (around one per month), frequent (every few days), or chronic (every other day). 2 Changes within the interactions between nerves and blood vessels lead to migraine headaches. chronic forms evolve from episodic types, and may coexist with migraine.

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